Dangers on the road include many different factors. The leading causes are people themselves. Distracted driving and driving under the influence are the biggest causes of fatal accidents. Speeding is also another cause. These are all avoidable actions by drivers. Some factors drivers have no control over such as weather, road conditions, and some auto malfunction issues although you should always keep up yearly maintenance on your vehicle to keep it in the best working condition. Checking out this map from the team at Teletracnavman.com, you can see exactly where the most dangerous car routes in America are.
You can also see the most common month, day of the week, date, and time the fatal crash occurs for each of the top 25 roads listed. Major interstates that span that up and down the coasts have the most fatalities. There is also I35 which runs from the US/Canadian border all the way down to Texas. It isn't until Dallas that I35 becomes one of the top 25 deadliest roads in the US. Florida also has 4 of the 25 most dangerous roads across their cities making it the leading state for automobile accidents.