Diphenhydramine (known as Benadryl) is an antihistamine mainly used to relieve symptoms of allergies, such as hay fever, hives, conjunctivitis, and reactions to insect stings or bites. Also, it is prescribed to patients with insomnia, motion sickness, and Parkinson's disease. Along with its healing effects, it sometimes provokes side effects, as you can see in the infographic.
AddictionResource authors clarify the things to avoid during Benadryl therapy. Firstly, stay away from alcohol. This combination can lead to severe, even life-threatening side effects.
Secondly, manage drug interactions. Tell your doctor or pharmacist about other medicines you are using, including prescription and non-prescription ones, vitamins, dietary and herbal supplements. Diphenhydramine may interact with some other drugs including antidepressants, benzodiazepines, and antipsychotics. As a result, it may decrease the effects of both drugs, change the time of Benadryl action, or increase the risk of side effects.
Thirdly, be cautious if some unwanted effect impairs your work. You may experience blurred vision or drowsiness and dizziness. Do not drive, use machinery, or do any activity that requires clear vision and alertness until you are sure you can perform it safely.
Fourthly, do not take Diphenhydramine if you are pregnant. It is rarely used during pregnancy, only if the benefit outweighs the risk.